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Table 3 Possible predictor for level VI metastasis in male patients with oral squamous cell carcinoma at the floor of mouth

From: Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth

Variables

level VI metastasis

p

Positive (n = 13)

Negative (n = 329)

Age

 <40 years

0

30 (9.1%)

 

  ≥ 40 years

13 (100%)

299 (90.9%)

0.392

cT stage

 T1 + T2

0

157 (47.7%)

 

 T3 + T4

13 (100%)

172 (52.3%)

0.001

cN

 N0

0

150 (45.6%)

 

 N1 + N2

9 (69.2%)

146 (44.4%)

 

 N3

4 (30.8%)

33 (10.3%)

0.002

PNIa,d

 Positive

6 (46.2%)

66 (20.1%)

 

 Negative

7 (53.8%)

198 (60.2%)

0.107

LVIb,e

 Positive

9 (69.2%)

50 (15.2%)

 

 Negative

4 (30.8%)

210 (63.8%)

< 0.001

Differentiation

 Well

3 (23.1%)

148 (45.0%)

 

 Moderate

5 (38.5%)

115 (35.0%)

 

 Poor

5 (38.5%)

66 (20.1%)

0.210

ENEc, f

 Positive

13 (100%)

25 (7.6%)

 

 Negative

0

199 (60.5%)

< 0.001

  1. a PNI perineural invasion, b LVI lymphovascular invasion, c ENE extranodal extension
  2. d Status of PNI in 65 (19.8%) patients remained unknown;
  3. e Status of LVI in 69 (21.0%) patients remained unknown;
  4. f Status of ENE in 105 (31.9%) patients remained unknown