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Table 4 The result of COX analysis of APE1 and the abundance of TILs with RFS in GEO databases

From: APE1 may influence CD4+ naïve T cells on recurrence free survival in early stage NSCLC

 

HR(95% CI)

P

HR(95% CI)*

P*

APE1

1.410 (1.130–1.760)

0.002

1.270 (1.007–1.603)

0.044

T cells CD4 naive

0.101 (0.021–0.474)

0.004

0.243 (0.048–1.224)

0.086

T cells CD8

0.217 (0.031–1.530)

0.125

  

B cells memory

0.007 (0.000–5.560)

0.146

  

T cells

0.871 (0.697–1.090)

0.226

  

NK cells

1.280 (0.860–1.900)

0.226

  

T cells follicular helper

2.890 (0.425–19.700)

0.278

  

B lineage

0.942 (0.842–1.050)

0.296

  

Cytotoxic lymphocytes

1.020 (0.866–1.210)

0.779

  

NK cells activated

0.899 (0.048–16.900)

0.943

  

CD8-C4-GZMK/CD8-C6-LAYN ratio

0.282 (0.138–0.577)

0.001

  

TNFRSF9+ Treg

2.140 (1.244–3.683)

0.006

  
  1. *Adjusted by sex (Male vs Female), age and clinical stage (II vs I and III + IV vs I) and histology (Squamous vs Adenocarcinoma and Others vs Adenocarcinoma)