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Table 1 Characteristics of the women with multizonal anogenital neoplasia assessment included in this study (n=253)

From: Multizonal anogenital neoplasia in women: a cohort analysis

Parameter Descriptive statisticsa
Age at first visit (years) median (IQR) 47 (36-56)
Duration of the follow-up (months) median (IQR) 12 (21)
Previous cervical HSIL/cancer, n (%) 94/251 (37)
Previous vulval HSIL/cancer, n (%) 91 (36)
Previous vaginal HSIL/cancer, n (%) 16 (6)
Previous anal HSIL/cancer, n (%) 62 (25)
Previous perianal HSIL/cancer, n (%) 34 (13)
Previous history of anogenital tract HSIL/cancer any site, n (%) 191(75)
 One site HSIL/cancer, n (%) 112 (59)
 Two sites HSIL/cancer, n (%) 61 (32)
 Three sites HSIL/cancer, n (%) 14 (7)
 Four sites HSIL/cancer, n (%) 3 (1.5)
 Five sites HSIL/cancer, n (%) 1 (0.5)
Previous anogenital cancer/per patient, n (%) 51 (20)
 Cervical 9
 Vulval 16
 Anal 21
 Perianal 8
 One anogenital cancer site, n (%) 48 (94)
 Two anogenital cancers sites, n (%) 3 (6)
Ever smoking, n (%) 133/235 (57)
Current smoking, n (%) 89/240 (37)
HIV-positive, n (%) 33 (13)
Pharmacologically immunocompromised, n (%) 35 (14)
Anal sexual intercourse, n (%) 37/128 (29)
MZN at first visit and/or follow-up, n (%) 56 (22)
Referral Centre first visit (n=253)/ MZN assessment first visit (n=252)
 MZN diagnosis, n (%) 50/252 (20)
 Any site with HSIL/cancer 107 (42)
 HSIL/cancer diagnosis in a new site/per patient, n (%) 53 (21)
 Anogenital cancers/per patient, n (%) 9 (4)
 New cases (in other sites) anogenital cancers/per patient, n (%) 6 (2)
Patients with follow-up (n=184)/ MZN assessment follow-up (n=180)
 MZN diagnosis, (%) 20/180 (11)
 New MZN diagnosis, n (%) 6/180 (3)
 Any site with HSIL/cancer, n (%) 50 (27)
 New HSIL/cancer in new areas/per patient, n (%) 32 (17)
 Anogenital cancers/per patient, n (%) 4 (2)
 New anogenital cancers (in other sites)/per patient, n (%) 4 (2)
  1. HSIL High-grade squamous intraepithelial lesions, IQR Interquartile range, MZN Multizonal anogenital neoplasia, SD Standard deviation
  2. aMedian (IQR) reported for continuous variables while N (%) are reported for categorical variables. The % for categorical variables is calculated using 253 as the denominator unless otherwise specified in the cell. Denominator may vary due to missing data