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Table 2 Univariate and multivariate analysis of overall survival in all breast cancer patients

From: Treatment patterns and outcomes in older women with early breast cancer: a population-based cohort study in China

Variable

Univariate analysis

Multivariate analysis

HRa (95% CI)

P-value

HRa (95% CI)

P-value

Age, years

 65–74

1

 

1

 

  ≥ 75

2.074 (1.442–2.983)

<  0.001

1.935 (1.109–3.376)

0.020

BMI, kg/m2

 18.5–23.9

1

 

1

 

  < 18.5

2.995 (1.586–5.655)

0.001

3.262 (1.526–6.974)

0.002

  > 23.9

1.161 (0.731–1.844)

0.527

0.918 (0.498–1.693)

0.784

Histology

 DCIS

1

   

 IDC

1.611 (0.817–3.177)

0.169

  

 Other

1.313 (0.544–3.169)

0.545

  

Clinical stage

 0-I

1

 

1

 

 II

1.172 (0.704–1.951)

0.542

1.089 (0.453–2.616)

0.850

 III

5.275 (3.259–8.538)

<  0.001

6.215 (2.713–14.235)

<  0.001

HR status

 Negative

1

 

1

 

 Positive

0.672 (0.471–0.958)

0.028

0.748 (0.442–1.269)

0.282

HER2 status

 Negative

1

   

 Positive

1.167 (0.685–1.990)

0.570

  

Ki-67 level

 Low (≤ 20%)

1

 

1

 

 High (>  20%)

2.102 (1.441–3.064)

< 0.001

1.900 (1.065–3.388)

0.030

Grade

 I-II

1

 

1

 

 III

1.747 (1.105–2.760)

0.017

1.047 (0.582–1.883)

0.879