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Table 1 Demographic and tumor characteristics of patients by age group

From: Treatment patterns and outcomes in older women with early breast cancer: a population-based cohort study in China

Characteristics

Total

Older group

Elderly group

P

N = 1094

N = 930

N = 164

n (%)

n (%)

n (%)

Age at diagnosis (years)

 Median (range)

68 (65–94)

68 (65–74)

77 (75–94)

 

Body mass index (Kg/m2)

   

<  0.001

 Underweight (<  18.5)

48 (4.4)

33 (3.5)

15 (9.1)

 

 Normal (18.5–23.9)

440 (40.2)

370 (39.8)

70 (42.7)

 

 Overweight (24.0–27.9)

310 (28.3)

278 (29.9)

32 (19.5)

 

 Obese (≥ 28.0)

94 (8.6)

86 (9.2)

8 (4.9)

 

 Unknowna

202 (18.5)

163 (17.5)

39 (23.8)

 

Histology

   

0.248

 DCIS

86 (7.9)

68 (7.3)

18 (11.0)

 

 IDC

863 (78.9)

739 (79.5)

124 (75.6)

 

 Other

97 (8.9)

81 (8.7)

16 (9.8)

 

 Unknowna

48 (4.4)

42 (4.5)

6 (3.7)

 

Clinical stage

   

0.440

 0-I

269 (24.6)

223 (24.0)

46 (28.0)

 

 II

511 (46.7)

441 (47.4)

70 (42.7)

 

 III

269 (24.6)

230 (24.7)

39 (23.8)

 

 Unknowna (I-III)

45 (4.1)

36 (3.9)

9 (5.5)

 

T stage

   

0.455

  ≤ T1

394 (36.0)

333 (35.8)

61 (37.2)

 

 T2

525 (48.0)

454 (48.8)

71 (43.3)

 

 T3-T4

125 (11.4)

103 (11.1)

22 (13.4)

 

 Unknowna

50 (4.6)

40 (4.3)

10 (6.1)

 

N stage

   

0.109

 N0

583 (53.3)

485 (52.2)

98 (59.8)

 

 N1

302 (27.6)

260 (28.0)

42 (25.6)

 

 N2

112 (10.2)

103 (11.1)

9 (5.5)

 

 N3

97 (8.9)

82 (8.8)

15 (9.1)

 

HR status

   

0.815

 Positive

757 (69.2)

641 (68.9)

116 (70.7)

 

 Negative

305 (27.9)

260 (28.0)

45 (27.4)

 

 Unknowna

32 (2.9)

29 (3.1)

3 (1.8)

 

HER2 status

   

0.127

 Positive

153 (14.0)

137 (14.7)

16 (9.8)

 

 Negative

776 (70.9)

658 (70.8)

118 (71.9)

 

 Unknowna

165 (15.1)

135 (14.5)

30 (18.3)

 

Subtype

   

0.329

 HR + HER2-

584 (53.4)

499 (53.7)

85 (51.8)

 

 HR + HER2+

76 (6.9)

68 (7.3)

8 (4.9)

 

 HR-HER2+

77 (7.0)

69 (7.4)

8 (4.9)

 

 HR-HER2-

188 (17.2)

155 (16.7)

33 (20.1)

 

 Unknowna

169 (15.4)

139 (14.9)

30 (18.3)

 

Ki-67 level

   

0.654

 Low (≤ 20%)

466 (42.6)

400 (43.0)

66 (40.2)

 

 High (>  20%)

467 (42.7)

396 (42.6)

71 (43.3)

 

 Unknowna

161 (14.7)

134 (14.4)

27 (16.5)

 

Grade

   

0.594

 I-II

337 (30.8)

292 (31.4)

45 (27.4)

 

 III

373 (34.1)

318 (34.2)

55 (33.5)

 

 Unknowna

384 (35.1)

320 (34.4)

64 (39.0)

 
  1. Abbreviations: DCIS ductal carcinoma in situ, IDC invasive ductal carcinoma, HR hormone receptor, HER2 human epidermal growth factor receptor 2
  2. a: Unknown values were excluded during chi-square tests