Fig. 2From: A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancerGenomic landscape of Chinese CRC patients using NGS. a Genomic landscape of 430 patients. The panel on the top shows the effects of the mutations at translational level while the panel at the bottom shows the MSI status, gender and age of each patient. The top 11 most frequently mutated genes are shown on the left. b Genomic landscape of the 98 tumors that were analyzed for MMR/MSI by IHC, PCR, and NGS. The bottom panel illustrates the MMR or MSI detection results for each patientBack to article page