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Fig. 1 | BMC Cancer

Fig. 1

From: A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer

Fig. 1

Patient Flow. Tissue samples were collected from 430 eligible CRC patients and subjected to genomic profiling using NGS. Of the 430 samples, 98 were also examined for MMR/MSI status using IHC and PCR. NGS MSI method was validated against IHC and PCR. The distribution of TMB between MSS and MSI-H tumors were also investigated using both the 98-patient cohort and the TCGA CRC cohort

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BMC Cancer

ISSN: 1471-2407

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