Table 2 Univariate and multivariate analysis of DFS
Number of patients | Median DFS, months | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|---|
p value | HR | 95% CI | p value | HR | 95% CI | |||
Primary tumor | ||||||||
Colon | 44 | 36 | 0.14 | 1.53 | 0.87–2.68 | |||
Rectum | 31 | 18 | ||||||
Primary nodal status | ||||||||
N0 | 31 | 37 | 0.034 | 1.73 | 1.04–2.88 | 0.008 | 2.01 | 1.20–3.34 |
N1/2 | 43 | 14 | ||||||
Time between primary and hepatic resection | ||||||||
< 12 months | 27 | 14 | 0.11 | 0.63 | 0.35–1.12 | |||
> 12 months | 48 | 28 | ||||||
Number of CRLM | ||||||||
< 5 | 70 | 28 | 0.005 | 4.58 | 1.58–13.26 | 0.001 | 6.49 | 2.15–19.61 |
> 5 | 4 | 7.5 | ||||||
Size of greatest CRLM | ||||||||
< 5 cm | 62 | 20 | 0.27 | 1.62 | 0.68–3.82 | |||
> 5 cm | 9 | 29 | ||||||
Neoadjuvant CTx | ||||||||
No | 62 | 20 | 0.62 | 0.83 | 0.39–1.76 | |||
Yes | 13 | 28 | ||||||
Additive CTx | ||||||||
No | 41 | 18 | 0.29 | 0.74 | 0.42–1.29 | |||
Yes | 34 | 29 | ||||||
CEA, ng/ml | ||||||||
< 70 | 47 | 28 | 0.70 | 0.76 | 0.18–3.19 | |||
> 70 | 5 | 19.5 | ||||||