Prognostic impact of additive chemotherapy after curative resection of metachronous colorectal liver metastasis: a single-centre retrospective study

Table 1 Patient demographics and clinical characteristics

	Total (n = 75)		Resection only (n = 41)		Resection plus additive CTx (n = 34)		p value
	n	%	n	%	n	%	p value
Age, years
Median	65		65		65		ns
Range	35–85		42–84		35–85
Sex
Male	48	64.0	25	61.0	23	67.6	ns
Female	27	36.0	16	39.0	11	32.4
Primary tumor
Colon	44	58.7	23	56.1	21	61.8	ns
Right	14	31.8	4	17.4	10	47.6
Left	30	68.2	19	82.6	11	52.4
Rectum	31	41.3	18	43.9	13	38.2
Primary nodal status
N0	31	45.9	14	34.1	17	50.0	ns
N1/2	43	54.1	27	65.9	16	47.1
Time between primary and hepatic resection
< 12 months	28	36.5	14	34.1	14	39.4	ns
> 12 Months	47	63.5	27	65.9	20	60.6
CEA before hepatic resection, ng/ml
Median	22.97		22.86		23.12		ns
Range	1.1–150		1.6–150		1.1–137
Number of CRLM
< 5	70	93.3	38	92.7	32	88.2	ns
> 5	4	5.3	3	7.3	1	2.9
Size of greatest CRLM
< 5 cm	62	82.7	32	78.0	30	88.2	ns
> 5 cm	9	12.0	6	14.6	3	8.8
Neoadjuvant CTx
No	62	81.1	35	85.4	27	79.4	ns
Yes	13	18.9	6	14.6	7	20.6
Surgical procedure
Minor liver resection	27	36.0	16	39.0	11	32.4	ns
Major liver resection	48	64.0	25	61.0	23	67.6

ISSN: 1471-2407