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Table 2 Univariate and multivariate analyses of factors associated with overall survival

From: A preoperative nomogram predicts prognosis of patients with hepatocellular carcinoma after liver transplantation: a multicenter retrospective study

 

Overall survival

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Age, years

1.009

0.984–1.036

0.475

   

Sex (male/female)

1.120

0.515–2.439

0.775

   

Smoking (yes/no)

1.266

0.801–2.000

0.313

   

Drinking (yes/no)

1.472

0.926–2.342

0.102

   

BMI, kg/m2

0.999

0.995–1.003

0.613

   

Hypertension (absence/ presence)

1.211

0.665–2.204

0.531

   

Diabetes (absence/ presence)

1.339

0.687–2.610

0.391

   

Ascites (absence/ presence)

1.473

1.079–2.011

0.015

1.132

0.802–1.598

0.480

HbsAg (negative/positive)

1.535

0.667–3.534

0.314

   

HbeAg (negative/positive)

1.696

1.056–2.725

0.029

1.640

1.014–2.651

0.044

Blood-type compatibility (matched/unmatched)

2.252

1.378–3681

0.001

1.733

1.034–2.880

0.034

Liver transplantation criteria

1.678

1.279–2.203

0.000

1.536

1.157–2.037

0.003

MELD score

1.058

1.019–1.100

0.004

1.044

1.003–1.088

0.037

Child-Pugh classification

1.001

0.895–1.121

0.980

   

WBC, 10*9/L

1.036

0.996–1.077

0.078

   

HGB, g/L

1.004

0.996–1.013

0.313

   

PLT, 10*9/L

1.002

0.999–1.005

0.112

   

INR

0.574

0.295–1.119

0.103

   

Serum CRE, μmol/L

0.998

0.994–1.002

0.343

   

Serum AFP, ng/mL

1.000

1.000–1.000

0.082

   

Serum CEA, ng/mL

0.944

0.850–1.049

0.283

   

Serum CA125, U/L

1.000

0.999–1.001

0.613

   

Serum ALT, U/L

1.001

0.999–1.003

0.279

   

Serum AST, U/L

1.000

1.000–1.000

0.416

   

Serum ALP, U/L

0.999

0.997–1.001

0.190

   

Serum GGT, U/L

0.999

0.997–1.001

0.114

   

Serum TB, μmol/L

0.999

0.997–1.002

0.654

   

Serum ALB, g/L

1.005

0.966–1.046

0.795

   
  1. CI confidence interval, HR hazard ratio, BMI body mass index, MELD model for end-stage liver disease, WBC white blood cell, HGB hemoglobin, PLT platelets, INR international normalized ratio, CRE creatinine, AFP alpha fetoprotein, CEA carcino-embryonic antigen, CA125 carbohydrate antigen 125, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, TB total bilirubin, ALB albumin