Fig. 2
From: Distribution of chimeric antigen receptor-modified T cells against CD19 in B-cell malignancies
CAR-T distribution in the NCG mice. a. Flow diagram of the experiment. Mice were sacrificed at 3 h, day2, day8 and day15 after CAR-T infusion and the organs were collected to test the CAR gene copies. b. Changes of CAR-T cells in the organs over time (BM: bone marrow; MLN: Mesenteric Lymph nodes). c. Tissue exposure of CAR-T cells in NCG mice (AUC: Area under the curve; E/U: Epididymis/Uterus; T/O: Testis/Ovary; SI: Small Intestine; SC: Spinal Cord)