Table 5 Comparisons of mutation types across clinical IHC subtypes. Only breast cancers with at least one variant were counted
Subtype | Mutation type | Mean | SD | Min | Max |
|---|---|---|---|---|---|
HR+/HER2+ | CNA | 1.1 | 0.6 | 0 | 3 |
FUSION | 0.1 | 0.3 | 0 | 1 | |
INFRAME | 0.0 | 0.0 | 0 | 0 | |
MISSENSE | 0.7 | 1.0 | 0 | 4 | |
OTHER | 0.2 | 0.7 | 0 | 4 | |
TRUNCATION | 0.1 | 0.2 | 0 | 1 | |
HR+/HER2- | CNA | 0.3 | 0.5 | 0 | 2 |
FUSION | 0.1 | 0.5 | 0 | 4 | |
INFRAME | 0.0 | 0.2 | 0 | 2 | |
MISSENSE | 1.9 | 5.0 | 0 | 32 | |
OTHER | 0.9 | 7.2 | 0 | 64 | |
TRUNCATION | 0.1 | 0.4 | 0 | 2 | |
HR−/HER2+ | CNA | 1.9* | 3.4 | 0 | 16 |
FUSION | 0.0 | 0.0 | 0 | 0 | |
INFRAME | 0.0 | 0.0 | 0 | 0 | |
MISSENSE | 6.5* | 17.4 | 0 | 64 | |
OTHER | 0.1 | 0.5 | 0 | 3 | |
TRUNCATION | 0.9* | 3.6 | 0 | 16 | |
HR−/HER2- | CNA | 1.4 | 3.9 | 0 | 16 |
FUSION | 0.0 | 0.0 | 0 | 0 | |
INFRAME | 0.1 | 0.4 | 0 | 2 | |
MISSENSE | 2.6 | 7.8 | 0 | 32 | |
OTHER | 2.1 | 7.8 | 0 | 32 | |
TRUNCATION | 0.2 | 0.8 | 0 | 4 |