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Fig. 5 | BMC Cancer

Fig. 5

From: Sequential and co-occurring DNA damage response genetic mutations impact survival in stage III colorectal cancer patients receiving adjuvant oxaliplatin-based chemotherapy

Fig. 5

Scatter plot of sequential somatic mutations associated with clinical outcomes. The sequential genetic order of KRAS, APC with APC, KRAS and BRCA2, APC with APC, BRCA2 has a different impact on recurrence-free survival. KRAS, APC and BRCA2, APC were associated with RFS; APC, KRAS and APC, BRCA2 were not. The p-value was calculated using the hazard ratio. Red dots represent the statistical significance of the hazard ratio, and the size of the circle represents the percentage of patients with sequential somatic mutations

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