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Fig. 3 | BMC Cancer

Fig. 3

From: Sequential and co-occurring DNA damage response genetic mutations impact survival in stage III colorectal cancer patients receiving adjuvant oxaliplatin-based chemotherapy

Fig. 3

CRC survival decision tree analysis. a A decision tree was generated to optimize risk stratification in our cohort. The internal nodes of the tree represent sequential somatic mutations. The leaf nodes represent recurrence-free survival for each subgroup, and each node is representative of at least ten patients. b Kaplan–Meier plot of the decision subgroups. Patients in the G1 subgroup had a higher probability of 4-year recurrence-free survival (probability = 0.88, 95% CI = 0.79–0.98) than patients in the G2 subgroup (probability = 0.46, 95% CI = 0.30–0.69). The hazard ratio was 5.80 (95% CI = 2.30–14.61), and the log-rank p-value was 2e-05 (median recurrence-free survival, NA months [95% CI, NA-NA] vs 33.47 months [95% CI, 23.63-NA] (G1 = C1 + C2 + C3, G2 = C4 + C5 + C6 + C7)

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BMC Cancer

ISSN: 1471-2407

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