A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates

Table 3 Linear Regressions on Quintiles

Parameter Estimates			Model Parameters
Parameter	Estimate (C.I.)	P-Value	R-Squared	F	dF	P-Value
*Quintiles*
*lm(Cancer_Rate ~ Quintile)*
Quintile 2	0.2 (−0.29, 0.69)	0.4242	0.04527	9.34	4745	2.27E-07
Quintile 3	0.14 (−0.35, 0.63)	0.5655
Quintile 4	0.72 (0.23, 1.2)	0.0042
Quintile 5	1.31 (0.82, 1.8)	1.8E-07
*Dichotomized Quintiles*
*lm(Cancer_Rate ~ Dichotomized_Quintiles)*
Upper_2_Quintiles	0.9 (0.58, 1.22)	3.9E-08	0.0383	30.9	1748	3.86E-08
*Dichotomized Quintiles Over Time*
*lm(Cancer_Rate ~ Year + Dichotomized_Quintiles)*
Upper_2_Quintiles	0.9 (0.59, 1.2)	1.1E-08	0.111	47.8	2747	< 2E-16
*lm(Cancer_Rate ~ Year: Dichotomized_Quintiles)*
Lower_3_Quintiles	0.139 (0.1, 0.17)	1.2E-14	0.111	47.7	2747	< 2E-16
Upper_2_Quintiles	0.1395 (0.1, 0.17)	1.0E-14

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