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Table 2 Linear Models: TPCIR Against Time, Cannabis, Cannabinoids and Ethnicity

From: A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates

Parameter Estimates Model Parameters
Parameter Estimate (C.I.) Pr(>|t|) R-Squared F dF P
lm(Cancer_Rate ~ Time)
 Year 0.14 (0.1, 0.17) 3.8E-14 0.0725 59.6 1748 3.80E-14
lm(Cancer_Rate ~ Cannabis)
 mrjmon 1.00 (−1.22, 3.22) 0.3800 −0.0003 0.78 1748 0.3770
lm(Cancer_Rate ~ Δ9THC)
 Δ9THC 0.33 (0.15, 0.5) 0.0002 0.0169 13.8 1748 0.0002
lm(Cancer_Rate ~ Exposure * Drug)
 Drug_Rate: Cannabis 4.63 (2.11, 7.15) 0.0003 0.0207 9.82 93,740 5.39E-15
 Drug_Rate: Alcohol −3.22 (−6.21, −0.22) 0.0356     
 Drug_Rate: Analgesics −6.63 (−10.51, −2.75) 0.0008     
 Cocaine −1.06 (− 1.63, −0.49) 0.0003     
 Cannabis −1.32 (− 1.89, −0.74) 0.0000     
 Drug_Rate −3.63 (−4.86, −2.4) 0.0000     
lm(Cancer_Rate ~ Exposure * Cannabinoid)
 Cannabinol 6.54 (5.07, 8.01) < 2E-16 0.0402 18.9 72,992 < 2E-16
 Cannabigerol 7.65 (5.91, 9.38) < 2E-16     
 Drug_Rate 2.14 (1.55, 2.73) 0.0000     
 Cannabichromene 3.86 (0.29, 7.42) 0.0340     
 Drug_Rate: Cannabichromene −3.02 (−5.4, −0.63) 0.0130     
lm(Cancer_Rate ~ Ethnic_THC_Exposure * Ethnicity)
 Ethnic_THC_Exposure 0.14 (0.07, 0.21) 0.0001 0.0021 2.57 64,493 0.0174
 Asian-Am_THC_Exposure 0.28 (0.02, 0.55) 0.0360     
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