Table 12 Spatially- and Temporally- Lagged Spatiotemporal Models
Parameter | Estimate (C.I.) | R.R. (C.I.) | E-Values |
|---|---|---|---|
LINEAR REGRESSION | |||
 Cancer Rate Over Time | |||
  Year | 0.14 (0.1, 0.17) | 1.06 (1.04, 1.08) | 1.31, 1.27 |
 Cancer Rate by Δ9THC | |||
  Δ9THC | 0.33 (0.15, 0.5) | 1.15 (1.07, 1.23) | 1.55, 1.33 |
 Cancer Rate by Drug Rate | |||
  Drug_Rate: Cannabis | 4.63 (2.11, 7.15) | 6.83 (2.41, 19.41) | 13.15, 4.25 |
 Cancer Rate by Cannabinoid Over Time | |||
  Cannabinol | 6.54 (5.07, 8.01) | 15.54 (8.39, 28.78) | 30.58, 16.27 |
  Cannabigerol | 7.65 (5.91, 9.38) | 24.71 (11.96, 51.02) | 48.91, 23.41 |
  Drug_Rate | 2.14 (1.55, 2.73) | 2.45 (1.91, 3.14) | 4.34, 3.24 |
  Cannabichromene | 3.86 (0.29, 7.42) | 5.04 (1.14, 22.44) | 9.54, 1.51 |
 Cancer Rate by Ethnic Cannabis Exposure | |||
  Ethnic_THC_Exposure | 0.14 (0.07, 0.21) | 1.06 (1.03, 1.09) | 1.31, 1.20 |
  Asian-Am_THC_Exposure | 0.28 (0.02, 0.55) | 1.12 (1.01, 1.26) | 1.50, 1.10 |
 Legal Status | |||
  Decriminalized | 0.85 (0.44, 1.26) | 1.42 (1.20, 1.69) | 2..20, 1.69 |
  Liberal | 0.663 (0.35, 0.98) | 1.32 (1.15, 1.50) | 1.96, 1.58 |
  Legal | 1.3286 (0.47, 2.19) | 1.73 (1.21, 2.45) | 2.86, 1.72 |
 Cancer by Legal Status | |||
  Decriminalized | 0.78 (0.37, 1.19) | 1.38 (1.16, 1.64) | 2.11, 1.60 |
  Legal | 1.51 (0.68, 2.35) | 1.87 (1.33, 2.66) | 3.16, 1.98 |
 Cancer by Year * Status | |||
  Year: Decriminalized | 0.0003 (0.0001, 0.0005) | 1.00013 (1.00004, 1.00021) | 1.011, 1.006 |
 Cancer by Year * Dichotomized_Status | |||
  Year: Liberal | 0.0002 (0, 0.0004) | 1.00008 (1.00001, 1.00015) | 1.0090, 1.0035 |
MIXED EFFECTS REGRESSION | |||
 Additive Model | |||
  Cannabis | 5.34 (0.07, 10.6) | 4.11 (1.02, 16.59) | 7.70, 1.18 |
 Interactive Drugs Model | |||
  Cannabis | 72.88 (49.6, 96.15) | 5.02E+ 08 (8.45E+ 05, 2.97E+ 11) | 1.01E+ 09, 1.69E+ 06 |
  Cigarettes: Cannabis: Analgesics | 2788.19 (1676.17, 3900.2) | Infinity (2.40E+ 200, Infinity) | Infinity, Infinity |
 Full Interactive Model | |||
  Cannabis | 79.27 (56.77, 101.78) | 7.00E+ 09 (1.14E+ 07, 4.31E+ 12) | 1.40E+ 09, 2.27E+ 07 |
  Cigarettes: Cannabis: Analgesics | 2525.7 (1488.65, 3562.75) | Infinity (1.38E+ 185, Infinity) | Infinity, Infinity |
 Full Interactive Model with Cannabinoids | |||
  Cigarettes: Cannabigerol: Alcohol | 4741.19 (3077.86, 6404.51) | Infinity (Infinity, Infinity) | Infinity, Infinity |
  Δ9THC: Alcohol | 14.95 (7.74, 22.16) | 73.78 (9.31, 584.34) | 147.07, 18.12 |
  Cigarettes: Δ9THC | 26.57 (15.54, 37.6) | 2.09E+ 03 (87.97, 4.95E+ 04) | 4.18E+ 03, 175.45 |
GEOSPATIAL REGRESSION | |||
 Additive Model | |||
  Cannabis | 5.16 (2.26, 8.06) | 11.18 (2.89, 43.30) | 21.84,. 5.22 |
 3-Way Interactive model | |||
  Cannabis | 20.68 (7.02, 34.33) | 1.55E+ 04 (26.85, 9.01E+ 06) | 3.11E+ 04, 53.19 |
 4-Way Interactive model | |||
  Cannabis | 5.42 (2.34, 8.5) | 12.61 (2.99, 53.07) | 24.71, 5.45 |
 Interactive Full Model - 0 Lags | |||
  Cannabis | 45.67 (18.77, 72.56) | 6.00E+ 10 (1.07E+ 04, 3.45E+ 15) | 1.20E+ 120, 5.15E+ 04 |
  Cigarettes: Cannabis: Alcohol | 840.86 (416.29, 1265.44) | 1.09E+ 180 (2.07E+ 89, 5.78E+ 270) | Infinity, 4.14E+ 89 |
  Cigarettes: Cannabis: Analgesics | 966.38 (184.69, 1748.06) | 8.18E+ 206 (7.64E+ 39, Infinity) | Infinity, 1.52E+ 40 |
 Time Lagged Models | |||
  Full model - 4 Lags - Just Lagging Cannabis | |||
   Cigarettes: Cannabis: Analgesics | 261.1 (19.06, 503.15) | 8.26E+ 39 (0.07, 9.56E+ 80) | 1.65E+ 40, 1.00 |
  Full model - 6 Lags - Just Lagging Cannabis | |||
   Cannabis | 8.49 (1.47, 15.5) | 50.45 (1.98, 1.28E+ 03) | 100.41, 3.39 |
  Full Model - 1 Temporal Lag | |||
   Cannabis | 7.88 (1.7, 14.06) | 48.60 (2.32, 1.016E+ 03) | 96.68, 4.07 |
   Cigarettes: Cannabis: Alcohol | 182.23 (29.55, 334.9) | 1..00E+ 39 (2.45E+ 06, 4.07E+ 71) | 1.99E+ 39, 4.91E+ 06 |
  Full Model - 2 Temporal Lags | |||
   Cigarettes: Cannabis: Alcohol | 658.72 (396.6, 920.84) | 3.76E+ 140 (5.65E+ 84, 2.53E+ 196) | 7.58E+ 140, 1.13E+ 85 |
  Full Model - 4 Temporal Lags | |||
   Cigarettes: Cannabis: Alcohol | 472.69 (145.49, 799.88) | 9.42E+ 126 (2.81E+ 30, 3.15E+ 223) | 1.88E+ 127, 5.62E+ 30 |
 Space-Time Lagged Models | |||
  Full Model - 1 Spatial & 1 Temporal Lag | |||
   Cannabis: Analgesics | 110.36 (37.53, 183.19) | 2.51E+ 23 (9.78E+ 07, 6.48E+ 38) | 5.03E+ 23, 1.95E+ 08 |
  Cigarettes: Cannabis: Alcohol | 1688.83 (336.9, 3040.77) | Infinity (1.033E+ 72, Infinity) | Infinity, 2.07E+ 72 |
  Full Model - 2 Spatial & 2 Temporal Lags | |||
  Cigarettes: Cannabis: Alcohol: Analgesics | 3954.04 (1565.01, 6343.08) | Infinity (Infinity, Infinity) | Infinity, Infinity |
 Cannabinoid Models | |||
  Cannabinoids as Main Effects | |||
   Cigarettes: Δ9THC: Analgesics | 391 (181.28, 600.72) | 1.62E+ 84 (1.65E+ 39, 1.59E+ 129) | 3.24E+ 84, 3.30E+ 39 |
   Δ9THC: Alcohol | 116 (51.71, 180.29) | 1.11E+ 25 (1.68E+ 11, 7.41E+ 38) | 2.23E+ 25, 3.36E+ 11 |
   Cigarettes: Δ9THC: Cannabigerol: Alcohol | 4810 (2124.8, 7495.2) | Infinity (Infinity, Infinity) | Infinity, Infinity |
   Δ9THC: Cannabigerol | 109 (41.58, 176.42) | 2.45E+ 23 (7.67E+ 08, 7.83E+ 37) | 4.90E+ 23, 1.54E+ 09 |
   Δ9THC: Cannabigerol: Alcohol: Analgesics | 5640 (1680.8, 9599.2) | Infinity (Infinity, Infinity) | Infinity, Infinity |
   Cigarettes: Δ9THC | 9.01 (0.6, 17.42) | 87.15 (1.35, 5.61E+ 03) | 173.80, 2.04 |
 Cannabinoids as Main Effects - 2 Lags | |||
  Cannabigerol | 21.6 (9.29, 33.9) | 3.32E+ 04 (89.18, 1.23E+ 07) | 6.64E+ 04, 177.84 |
  THC: Alcohol | 10.25 (4.12, 16.37) | 139.58 (7.34, 2.65E+ 03) | 278.66, 14.15 |
  Cannabigerol: Alcohol: Analgesics | 1176.24 (308.66, 2043.82) | 1.66E+ 246 (9.51E+ 64, Infinity) | Infinity, 1.91E+ 65 |
 Cannabinoids as Main Effects - 4 Lags | |||
  Cigarettes: THC | 2.87 (1.47, 4.27) | 4.06 (2.06, 8.04) | 7.58, 3.52 |
  Cigarettes: Cannabigerol: Alcohol | 668.38 (191.09, 1145.67) | 5.01E+ 141 (5.21E+ 40, 4.82E+ 242) | 1.00E+ 142, 1.04E+ 41 |
 Cannabinoids as Main Effects - 6 Lags | |||
  Cigarettes: THC | 28.16 (18.61, 37.71) | 7.61E+ 05 (7.76E+ 03, 7.46E+ 07) | 1.52E+ 06, 1.55E+ 04 |
  THC: Cannabigerol | 46.22 (30.06, 62.38) | 4.50E+ 09 (1.92E+ 06, 1.06E+ 13) | 9.01E+ 09, 3.84E+ 06 |
  Cigarettes: Cannabigerol: Alcohol | 724.22 (143.74, 1304.71) | 1.82E+ 151 (1.84E+ 30, 1.80E+ 272) | 3.64E+ 151, 3.68E+ 30 |
 Ethnicity Models | |||
  Cancer Incidence as a Function of Racial Cannabis Exposure | |||
   Afric-Am._THC_Exp: Hispan.Am_THC_Exp | 1.74 (1.18, 2.29) | 2.22 (1.72, 2.86) | 3.86, 2.86 |
   Afric-Am._THC_Exp: Hispan.Am_THC_Exp: Asian-Am._THC_Exp: AIAN-Am._THC_Exp | 0.15 (0.09, 0.21) | 1.51 (1.18, 1.91) | 2.38, 1.66 |
   Asian-Am._THC_Exp: AIAN-Am._THC_Exp | 0.89 (0.37, 1.41) | 1.06 (1.04, 1.10) | 1.34, 1.24 |