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Fig. 2 | BMC Cancer

Fig. 2

From: MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4

Fig. 2

Downregulation of miR-105-3p inhibits cell proliferation and promotes apoptosis of MCF-7 and ZR-75-30 cells. a MCF7 and ZR-75-30 cells were transfected with either NC inhibitor or miR-105-3p inhibitor for 72 h. a CCK-8 assay of the viability of MCF-7 and ZR-75-30 cells. b Scratch test. c TUNEL assay. d Western blot analysis of the related proteins involved in cell apoptosis, including Bax, Bcl-2, cleaved caspase-3, and cleaved caspase-9. Asterisks indicate significant differences from the control (**P < 0.01, Student’s t-test, compared to the NC inhibitor)

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