Table 4 Select characteristics of included benzene studies
Reference | Study design | Population or Cases / controls | Study setting | Years of follow-up | Adjusted for smoking |
|---|---|---|---|---|---|
Adegoke 2003 [37] | Population-based case-control | 236 AML cases; 79 CML cases 502 controls | China: Shanghai | 1987–1989 | No |
Albin 2003 [38] | Population-based case-control | 330 MDS cases 337 controls | Southern Sweden | 1976–1993 | Noa |
Blair 2001 [39] | Population-based case-control | 132 AML cases; 46 CML cases; 58 MDS cases 1087 controls | USA: Iowa and Minnesota | 1976–1993 | Yes |
Bjork 2001a [40] | Population-based case-control | 226 CML cases 251 controls | Southern Sweden | 1980–1984 | No* |
Bonzini 2019 [41] | Occupational cohort | 5112 oil refinery workers | Italy | 1976–1993 | No |
Collins 2015 [42] | Occupational cohort | 2266 chemical workers | USA: Michigan | 1944–1977 | No |
Copley 2017 [43] | Hospital-based case control | 604 MDS cases 1193 controls | China: Shanghai | 2003–2007 | Noa |
Costantini 2008 [44] | Population-based case-control | 142 AML cases 893 controls | Italy | 1991–1993 | Noa |
Divine 1999 [45] | Occupational cohort | 28,480 oil refinery and petrochemical workers | USA: Texas | 1947–1993 | No |
Divine 2000 [46] | Occupational cohort | 24,124 oil production and pipeline workers | USA | 1946–1994 | No |
Guenel 2002 [47] | Nested case-control | 26 AML cases 103 controls | France | 1978–1989 | No |
Huebner 2009 [48] | Occupational cohort | 127,266 petroleum workers | USA: Louisiana and Texas | 1979–2000 | No |
Ireland 1997 [49] | Occupational cohort | 4172 chemical workers | USA: Illinois | 1940–1991 | No |
Kirkeleit 2008 [50] | Occupational case-control | 27,919 upstream petroleum workers | Norway | 1981–2003 | No |
Linet 2015 [51] | Occupational cohort | 73,789 benzene-exposed and 34,405 unexposed workers | China | 1972–1999 | No |
McCraw 1985 [52] | Occupational cohort | 3976 oil refinery workers | USA: Illinois | 1973–1982 | No |
Poynter 2017 [53] | Population-based case-control | 420 AML cases; 265 MDS cases 1388 controls | USA: Minnesota | 2010–2014 | Yes |
Rhomberg 2016 [54] | Occupational cohort | 1696 Pliofilm workers | USA: Ohio | 1940–1996 | No |
Rushton 2014 [55] | Nested case-control | 60 AML cases 241 controls | Canada, UK, and Australia | 1950–2006c | No |
Saberi Hosnijeh 2013 [33] | Population-based cohort | 241,465 adults (European Prospective Investigation into Cancer and Nutrition cohort) | 10 European countries: Denmark, France, Greece, Germany, Italy, The Netherlands, Norway, Spain, Sweden, and the UK | 1992–2010 | Yes |
Sathiakumar 1995 [56] | Occupational case-control | 10 AML cases; 5 CML cases; 42 controls | USA | 1976–1990 | No |
Satin 1996 [57] | Occupational cohort | 17,844 Port Arthur oil refinery workers | USA: Texas | 1937–1987 | No |
Schnatter 2012 [58] | Occupational case-control | 29 MDS cases; 60 AML cases; 30 MPD cases; 28 CML cases 616 controls | Canada, UK, and Australia | 1950–2006c | Noa |
Stenehjem 2015 [59] | Occupational cohort | 4 MDS cases; 10 AML cases; 3 CML cases b 1661 controls | Norway | 1999–2011 | Yes |
Strom 2005 [60] | Hospital-based case-control | 354 MDS cases 452 controls | USA: Texas | 1999–2003 | Yes |
Talibov 2014 [34] | Population-based case-control | 14,982 AML cases 74,505 controls | 4 Nordic countries: Finland, Norway, Sweden, and Iceland | 1960–2005c | No |
Teras 2019 [61] | Population-based cohort | 115,996 adults (American Cancer Prevention Study-II Nutrition cohort) | USA | 1997–2013 | Yes |
Wong 1993 [62] | Occupational cohort | 18,135 gasoline distribution workers | USA | 1946–1986 | No |
Wong 2001a [63] | Occupational cohort | 7543 petroleum refinery workers | USA: Texas | 1945–1996 | No |
Wong 2001b [64] | Occupational cohort | 3328 petroleum refinery workers | USA: California | 1959–1997 | No |
Wong 2010 [65] | Hospital-based case-control | 722 AML cases 1444 controls | China: Shanghai | 2003–2007 | No |