Table 3 Efficacy of apatinib in patients with BTC
Parameter | Total(n = 28) n (%) | Monotherapy(n = 12) n (%) | Combination therapy(n = 16) n (%) | P |
|---|---|---|---|---|
Best response | 0.478 | |||
CR | 0 (0) | 0 (0) | 0 (0) | |
PR | 6 (21.4) | 2 (16.7) | 4 (25.0) | |
SD | 15 (53.6) | 8 (66.6) | 7 (43.8) | |
PD | 7 (25.0) | 2 (16.7) | 5 (31.2) | |
ORR | 6 (21.4) | 2 (16.7) | 4 (25.0) | 0.595 |
DCR | 21 (75.0) | 10 (83.3) | 11 (68.8) | 0.378 |
Median PFS (months) | 4.3 | 4.2 | 4.9 | 0.867 |
Median OS (months) | 6.2 | 7.0 | 6.1 | 0.871 |