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Table 1 Patient and treatment characteristics

From: The efficacy and safety of apatinib treatment for patients with advanced or recurrent biliary tract cancer: a retrospective study

Characteristic

Total(n = 28)

n (%)

Monotherapy(n = 12)

n (%)

Combination therapy(n = 16)

n (%)

P

Age (years, median)

54 (36–79)

52 (36–79)

57 (43–64)

 

Sex

 Female

12 (42.9)

5 (41.7)

7 (43.8)

0.912

 Male

16 (57.1)

7 (58.3)

9 (56.2)

 

ECOG

 0–1

22 (78.6)

10 (83.3)

12 (75.0)

0.595

 2

6 (21.4)

2 (16.7)

4 (25.0)

 

Primary tumor site

 GBC

9 (32.1)

3 (25.0)

6 (37.5)

0.483

 CCA

19 (67.9)

9 (75.0)

10 (62.5)

 

Metastatic site

 Intra-abdominal lymph node

16 (57.1)

6 (50.0)

10 (62.5)

 

 Liver

14 (50.0)

2 (16.7)

12 (75.0)

0.086

 Peritoneum

8 (28.6)

3 (25.0)

5 (31.3)

 

 Lung

8 (28.6)

6 (50.0)

2 (12.5)

 

 Others

16 (57.1)

7 (58.3)

9 (56.3)

 

Number of metastatic sites

 1–2

13 (46.4)

5 (41.7)

8 (50.0)

0.662

  ≥ 3

 Treatment line

15 (53.6)

7 (58.3)

8 (50.0)

 

 2

11 (39.3)

5 (41.7)

6 (37.5)

0.823

 3–4

17 (60.7)

7 (58.3)

10 (62.5)

 
  1. ECOG Eastern Cooperative Oncology Group performance status, GBC gallbladder cancer, CCA Cholangiocarcinoma