Table 3 Multivariate Cox analysis of prognostic factors for OS, PFS, DFS. (OS: p = 0·0006, χ2 = 27·27; PFS: p = 0·065, χ2 = 19·35; DFS: p = 0·087, χ2 = 9·62)

KPS (80^a vs 90)

··

··

0.50 (0.20–1.22)

0.13

0.53 (0.21–1.36)

0.2

Complication (yes^a vs no)

1.70 (0.54–5.41)

0.37

1·56 (0·67–3·64)

0.3

··

··

Differentiation

··

0

··

0.06

··

0.6

 High^a

1

··

1

··

1

··

 Middle

3.07 (0.29–32.59)

0.35

1.60 (0.31–8.18)

0.57

1.48 (0.32–6.82)

0.6

 Low

26.87 (2.38–303.60)

0.01

4.75 (0.73–22.74)

0.07

2.39 (0.42–13.51)

0.3

ypN stage (N0^a vs N1 + N2)

0.31 (0.029–3.19)

0.32

0.41 (0.073–2.24)

0.3

··

··

ypTNM stage (0-IIB^a vs IIC-IIIC)

3.44 (0.82–14.38)

0.09

1.82 (0.67–4.99)

0.24

1.49 (0.53–4.16)

0.5

pCR (yes^a vs non)

0.40 (0.053–2.99)

0.37

1.18 (0.29–4.84)

0.81

··

··

MVR (non^a vs yes)

1.07 (0.28–4.14)

0.92

0.97 (0.40–2.36)

0.95

··

··

VLPNI (negative^a vs positive)

3.61 (0.84–15.54)

0.09

2.16 (0.77–6.02)

0.14

2.01 (0.64–6.37)

0.2

R0 resection (non-R0^a vs R0)

0.21 (0.030–1.48)

0.12

0.60 (0.12–3.08)

0.54

··

··