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Table 5 Adverse events reported with bevacizumab treatment

From: Bevacizumab for radiation necrosis following radiotherapy of brain metastatic disease: a systematic review & meta-analysis

Studies Patients Symptoms
Sadraei, et al. (2015) [54] 5 (29%) Grade 1: proteinuria (1).
Grade 2: hypertension (1), fatigue (1), urinary tract infection (1).
Grade 3: DVT/pulmonary embolism (1)
Zhuang, et al. (2015) [55] 2 (14%) Grade 1: mild allergy (1), hypertension (1)
Zhuang, et al. (2019) [33] 2 (9.5%) Grade 1: mild allergy (1), hypertension (1)
Tanigawa, et al. (2019) [56] 4(100%) Hypertension (3), proteinuria (3), edema (1)
Glitza, I. et al. (2017) [58] 1(14%) Arthralgia (1), dysgeusia (1)