Multi-omics analysis of genomics, epigenomics and transcriptomics for molecular subtypes and core genes for lung adenocarcinoma

Table 3 The top ten genes positively and negatively related to methylation for LUAD

Methylation probe	Expression-gene	Correlation	P-value	Z-value	Adjusted p-value
cg16550453	TDRD1	−0.95789	< 0.0001	−3.83943	< 0.0001
cg26600802	TDRD1	−0.94634	< 0.0001	−3.59094	< 0.0001
cg27547703	TDRD1	−0.91787	< 0.0001	−3.15072	< 0.0001
cg03669949	DDX43	−0.89925	< 0.0001	−2.93658	< 0.0001
cg04131456	TUBA3C	−0.89162	< 0.0001	− 2.85958	< 0.0001
cg18527919	FAM228A	−0.86751	< 0.0001	−2.64587	< 0.0001
cg04511534	GGT6	−0.86258	< 0.0001	−2.60665	< 0.0001
cg23504215	TDRD1	−0.8603	< 0.0001	−2.58903	< 0.0001
cg10088332	GTSF1	−0.85931	< 0.0001	−2.58142	< 0.0001
cg00215587	MKRN3	−0.85871	< 0.0001	−2.57679	< 0.0001
cg24809845	KCNK1	0.743871	< 0.0001	1.918181	< 0.0001
cg14853341	KCNK1	0.710646	< 0.0001	1.776976	< 0.0001
cg15817960	HOXC6	0.694593	< 0.0001	1.713553	< 0.0001
cg22702618	CRLF1	0.688322	< 0.0001	1.68952	< 0.0001
cg13299984	PRDM16	0.687689	< 0.0001	1.687116	< 0.0001
cg06714180	HOXC6	0.683554	< 0.0001	1.67151	< 0.0001
cg01062942	RASAL3	0.638808	< 0.0001	1.512315	< 0.0001
cg17126555	ICAM3	0.636795	< 0.0001	1.505528	< 0.0001
cg22987448	MYO1F	0.63079	< 0.0001	1.485454	< 0.0001
cg01336912	PALM3	0.625825	< 0.0001	1.469047	< 0.0001