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Table 1 Patients data

From: Metabolic alterations in meningioma reflect the clinical course

Parameter Cluster 1
N = 15
Cluster 2
N = 28
Significance level (p)
Sex (N,%)
 Male (N = 10) 2 (14.2%) 8 (28.5%) 0.45****
 Female (N = 33) 13 (86.6%) 20 (71.4%)  
Age (mean, SD) 62.3 ± 13.1 64.4 ± 12.8 0.62*
Size (cm3) (mean, SD) 48.3 ± 51.8 88.6 ± 103.3 0.09*
Peritumoral edema (N, %)
 high 4(26.6%) 18(64.3%) 0.02***
 low 11(73.4%) 10(35.7%)  
Location (N, %)
 falx 3(20%) 3(10.7%) 0.64****
 convexity 2(13.3%) 10(35.7%) 0.16****
 frontobasal 4(26.6%) 5(17.8%) 0.69****
 sphenoid wing 2(13.3%) 4(14.2%) 1***
 petroclival 1(6.6%) 1(3.5%) 1****
 spinal 2(13.3%) 1(3.5%) 0.11****
 others 1(6.6%) 4(14.2%) 0.64****
Simpson grade (N, %)
 Grade 1 5(33.3%) 7(25%) 0.74****
 Grade 2 9(60%) 16(57.1%) 1***
 Grade 3 0(0%) 3(10.7%) 0.54****
 Grade 4 1(6.6%) 2(7.1%) 1****
Preoperative KPS (median, 95% CI) 80% CI(70–80%) 70% CI(%60–80%) 0.01**
Postoperative KPS (median, 95% CI) 90% CI(80–90%) 70% CI(50–90%) 0.007**
Proliferation index (N, %)
 MIB1 < 5% 15(100%) 9(32.1%) 0.01****
 MIB1 > 5% 0(0%) 19(67.9%)  
Pathology (N, %)
 WHO grade I 15(100%) 13(46.4%) 0.001****
 WHO grade II + III 0(0%) 15(53.6%)  
  1. SD standard deviation
  2. CI confidence interval
  3. KPS Karnofsky score
  4. * T-test
  5. **Wilcoxon test
  6. ***Chi-squared test
  7. ****Fisher’s exact test