Table 1 Patients data
From: Metabolic alterations in meningioma reflect the clinical course
Parameter | Cluster 1 N = 15 | Cluster 2 N = 28 | Significance level (p) |
|---|---|---|---|
Sex (N,%) | |||
Male (N = 10) | 2 (14.2%) | 8 (28.5%) | 0.45**** |
Female (N = 33) | 13 (86.6%) | 20 (71.4%) | |
Age (mean, SD) | 62.3 ± 13.1 | 64.4 ± 12.8 | 0.62* |
Size (cm3) (mean, SD) | 48.3 ± 51.8 | 88.6 ± 103.3 | 0.09* |
Peritumoral edema (N, %) | |||
high | 4(26.6%) | 18(64.3%) | 0.02*** |
low | 11(73.4%) | 10(35.7%) | |
Location (N, %) | |||
falx | 3(20%) | 3(10.7%) | 0.64**** |
convexity | 2(13.3%) | 10(35.7%) | 0.16**** |
frontobasal | 4(26.6%) | 5(17.8%) | 0.69**** |
sphenoid wing | 2(13.3%) | 4(14.2%) | 1*** |
petroclival | 1(6.6%) | 1(3.5%) | 1**** |
spinal | 2(13.3%) | 1(3.5%) | 0.11**** |
others | 1(6.6%) | 4(14.2%) | 0.64**** |
Simpson grade (N, %) | |||
Grade 1 | 5(33.3%) | 7(25%) | 0.74**** |
Grade 2 | 9(60%) | 16(57.1%) | 1*** |
Grade 3 | 0(0%) | 3(10.7%) | 0.54**** |
Grade 4 | 1(6.6%) | 2(7.1%) | 1**** |
Preoperative KPS (median, 95% CI) | 80% CI(70–80%) | 70% CI(%60–80%) | 0.01** |
Postoperative KPS (median, 95% CI) | 90% CI(80–90%) | 70% CI(50–90%) | 0.007** |
Proliferation index (N, %) | |||
MIB1 < 5% | 15(100%) | 9(32.1%) | 0.01**** |
MIB1 > 5% | 0(0%) | 19(67.9%) | |
Pathology (N, %) | |||
WHO grade I | 15(100%) | 13(46.4%) | 0.001**** |
WHO grade II + III | 0(0%) | 15(53.6%) | |