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Table 2 Cox proportional hazards regression analyses of overall survival according to tumor recurrence

From: Preoperative nutritional risk index and postoperative one-year skeletal muscle loss can predict the prognosis of patients with gastric adenocarcinoma: a registry-based study

Variables

Whole group (N = 958)

Recurrence group (N = 293)

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

HR

95% CI

P-value

HR

95% CI

P-value

HR

95% CI

P-value

HR

95% CI

P-value

Clinicopathologic

 Age (continuous)

1.019

1.011–1.028

<  0.001

   

1.002

0.992–1.012

0.701

   

 Sex (male)

1.242

1.007–1.531

0.043

   

1.009

0.785–1.297

0.943

   

 BMI (continuous)

0.968

0.935–1.001

0.061

   

0.999

0.960–1.039

0.955

   

 CCI (continuous)

1.223

1.138–1.314

<  0.001

1.173

1.082–1.272

<  0.001

1.068

0.977–1.169

0.150

   

 TNM stage (stage 3)

1.927

1.573–2.362

<  0.001

1.324

1.054–1.663

0.016

1.528

1.175–1.987

0.002

1.312

0.998–1.724

0.051

 Operation type (open)

1.458

1.027–2.072

0.035

   

1.308

0.845–2.024

0.229

   

 Gastrectomy type (total)

1.240

1.020–1.506

0.030

   

1.109

0.875–1.405

0.393

   

 Tumor size (continuous)

1.079

1.052–1.108

< 0.001

   

1.022

0.990–1.055

0.173

   

 Tumor location (upper vs. others)

1.058

0.949–1.181

0.310

   

1.033

0.921–1.159

0.575

   

 Lauren’s classification (other types vs. intestinal)

0.929

0.814–1.060

0.272

   

1.245

1.073–1.445

0.004

1.157

0.989–1.354

0.069

 Recurrence

13.992

11.197–17.486

<  0.001

16.838

13.089–21.662

<  0.001

NA

NA

NA

NA

NA

NA

Preop. Body/Nutrition (as a continuous variable)

 SMI

1.000

0.994–1.006

0.965

   

1.001

0.995–1.007

1.001

   

 SFA

0.997

0.995–0.999

<  0.001

0.998

0.996–1.000

0.075

0.999

0.997–1.001

0.497

   

 VFA

1.000

0.998–1.002

0.864

   

0.999

0.997–1.001

0.447

   

 NRI

0.960

0.948–0.973

<  0.001

0.976

0.962–0.991

0.002

0.981

0.966–0.996

0.014

0.966

0.950–0.983

<  0.001

Body/Nutrition change (as a continuous variable)

 dSMI

1.043

1.019–1.066

<  0.001

1.060

1.035–1.085

<  0.001

1.045

1.019–1.071

<  0.001

1.045

1.019–1.073

<  0.001

 dSFA

1.000

0.998–1.003

0.816

   

1.004

1.002–1.007

0.002

1.005

1.002–1.008

0.002

 dVFA

1.000

0.998–1.002

0.881

   

1.001

0.998–1.003

0.660

   

 dNRI

1.000

0.993–1.006

0.917

   

1.004

0.995–1.002

0.406

   
  1. Abbreviations: HR Hazards ratio, CI Confidence interval, CCI Charlson comorbidity index, Preop Preoperative, SMA Skeletal muscle area, SMI Skeletal muscle index, SFA subcutaneous fat area, VFA Visceral fat area, NRI Nutritional risk index, dSMA Difference in SMA between before and one year after surgery, dSMI Difference in SMI between before and one year after surgery, dNRI Difference in NRI between before and one year after surgery
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BMC Cancer

ISSN: 1471-2407

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