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Table 2 Synchronic mutations co-occurring with KRAS G12C among NSCLC samples

From: Molecular profile of KRAS G12C-mutant colorectal and non-small-cell lung cancer

Genes

Amino acid change

Allelic frequency %)

EGFR

Exon 19 deletion (2 cases)

19 and 2.5

 

L858R (2 cases)

4 and 2

 

S768Ia

18

 

G719N

14

 

T725Mb/A597Pb/R831Hb/V774Mb

49/13/3/7

KRAS

G13D (2 cases)

49 and 36

 

G12S

17

 

G12V

4

 

Q22b

16

BRAF

V600Ea (2 cases)

7 and 5

 

V600K

20

 

G464Eb

15

NRAS

Q61K

24

 

G13V

14

 

E132Kb

NR

  1. a 1 case of co-existing KRAS G12C, EGFR S768I, and BRAF V600E; b non-canonical mutations. Abbreviation: NR not reported