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Table 4 Multivariable analysis stratifying by sex using cox regression and Fine&Gray regression models for predicting CSS in 560 localized RCC patients diagnosed with clear cell carcinoma

From: Distinct effect of body mass index by sex as a prognostic factor in localized renal cell carcinoma treated with nephrectomy ~ data from a multi-institutional study in Japan ~

Variables

Male

Female

Cox regression model

Fine&Gray regression model

Cox regression model

Fine&Gray regression model

HR

95% CI

P value

SHR

95% CI

P value

HR

95% CI

P value

SHR

95% CI

P value

Age (<65 vs ≥65 years)

0.74

0.36-1.49

0.396

0.53

0.23-1.21

0.134

1.69

0.59-4.81

0.324

0.45

0.06-3.36

0.438

ECOG Performance Status (0 vs ≥1)

4.59

1.84-11.45

0.001

4.49

1.81-11.13

0.001*

5.97

1.77-20.17

0.004*

4.60

1.09-19.40

0.038*

Pathological stage (1-2 vs >3)

4.26

2.13-8.50

<0.001*

4.45

2.02-9.81

<0.001*

3.17

1.07-9.37

0.037*

5.60

1.03-30.32

0.046*

Tumor size (<4 vs ≥4cm)

7.62

2.64-21.94

<0.001*

3.62

1.39-9.37

0.008*

2.77

0.57-13.56

0.208

22.86

1.05-499.7

0.047*

BMI (<25 vs >25)

0.39

0.15-1.04

0.059

0.22

0.06-0.80

0.022*

0.57

0.15-2.12

0.398

0.47

0.04-4.93

0.527

  1. CSS cancer-specific survival, OR odds rario, CI confidence interval, SHR sub-hazard ratio, ECOG eastern cooperative oncology group, BMI body mass index, *denotes p < 0.05