Skip to main content

Table 3 Analysis of clinical features

From: The value of lncRNAs as prognostic biomarkers on clinical outcomes in osteosarcoma: a meta-analysis

Outcome

No. of Studies

No. of Participants

OR (95% CI)

P value

Model

Heterogeneity

Chi2, P-value, I2

MALAT1

 Age

3

259

0.73 (0.43, 1.24)

0.24

Fixed

0.36, 0.84, 0%

 Gender

3

259

0.73 (0.44, 1.20)

0.21

Fixed

0.16, 0.92, 0%

 Clinical stage

3

259

1.48 (0.27, 7.94)

0.65

Random

15.91, 0.0004, 87%

 Tumor size

3

259

0.95 (0.50, 1.81)

0.89

Random

10.77, 0.005, 81%

 Distant metastasis

3

259

1.98 (0.32, 12.05)

0.46

Random

16.26, 0.0003, 88%

TUG1

 Age

5

294

1.2 (0.48, 3.02)

0.28

Fixed

1.97, 0.74, 0%

 Gender

5

294

1.02 (0.62, 1.65)

0.95

Fixed

2.97, 0.56, 0%

 Clinical stage

4

254

4.66 (2.47, 8.79)

<0.00001

Fixed

0.45, 0.93, 0%

 Tumor size

4

254

4.07 (2.33, 7.12)

<0.00001

Fixed

2.96, 0.4, 0%

 Distant metastasis

5

294

3.53 (1.20, 10.41)

0.02

Random

13.52, 0.009, 70%

XIST

 Age

2

209

1.18 (0.44, 3.15)

0.74

Random

2.55, 0.11, 61%

 Gender

3

249

0.91 (0.56, 1.50)

0.72

Fixed

1.56, 0.46, 0%

 Clinical stage

3

249

3.92 (2.31, 6.66)

<0.00001

Fixed

0.92, 0.63, 0%

 Tumor size

3

249

1.15 (0.41, 3.23)

0.80

Random

6.74, 0.03, 70%

 Distant metastasis

2

209

3.10 (1.61, 5.95)

0.0007

Fixed

0.58, 0.45, 0%

  1. CI confidence interval, OR odds ratio