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Table 3 Associations with overall survival and clinicopathologic characteristics in TCGA patients using Cox regression. b. Multivariate survival model after variable selection

From: Expression of BAG1 is associated with prognosis in kidney renal clear cell carcinoma based on bioinformatics

Clinicopathologic variable

HR (95% CI)

p-value

a

Age (continuous)

1.03 (1.02–1.05)

0.000 ***

BAG1 expression (Low vs. High)

2.11 (1.5–2.97)

0.000 ***

Grade

2.25 (1.83–2.77)

0.000 ***

Stage

1.94 (1.72–2.22)

0.000 ***

Cancer Status (tumor free vs. with tumor)

4.92 (3.52–6.91)

0.000 ***

Tumor size

1.90 (1.61–2.31)

0.000 ***

Lymph nodes (positive vs. negative)

3.41 (1.69–6.90)

0.000 ***

Distant metastasis (positive vs. negative)

4.43 (3.18–6.61)

0.000 ***

Gender (male vs. Female)

0.91 (0.65–1.31)

0.576

hemoglobin result (Low vs. Normal)

0.45 (0.30–0.66)

0.000 ***

history of neoadjuvant treatment (Yes vs. No)

2.37 (1.21–4.66)

0.012 *

Serum calcium (Low vs. High)

1.21 (0.81–1.61)

0.431

b

Tumor size

1.25 (0.72–2.17)

0.417

Lymph nodes (positive vs. negative)

1.71 (0.78–3.73)

0.175

Distant metastasis (positive vs. negative)

1.97 (0.79–4.91)

0.145

Stage

1.25 (0.67–2.32)

0.478

BAG1 expression (Low vs. High)

1.75 (1.05–2.90)

0.029*

  1. *:p < 0.05,**:p < 0.01,***:p < 0.001