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Table 1 Characteristics of patients with Gastroenteropancreatic Neuroendocrine Tumors and of their initial treatments, SEER-Medicare 1995–2010; Small Intestine Not Otherwise Specified: SI NOS; National Cancer Institute: NCI

From: Effect of treatment center volume on outcomes in gastroenteropancreatic neuroendocrine tumor patients

Characteristic low
(n = 331)
medium (n = 408) high
(n = 160)
p-value
Mean age (SD) 75.1 (7.3) 73.8 (7.1) 73.0 (6.2) 0.023
Median time to treatment (SD) 22.0 (47.5) 24.0 (41.8) 26.0 (55.1) 0.148
Male, n (%) 150 (45.3) 185 (45.3) 78 (48.8) 0.734
Race, n (%)     0.799
 white 280 (84.6) 344 (84.3) 137 (85.6)  
 black 26 (7.9) 38 (9.3) > 12 (> 7.5)  
 other 25 (7.6) 26 (6.4) < 11 (< 6.9)  
Primary site, n (%)     <.0001
 stomach 37 (11.2) 37 (9.1) < 11 (< 6.9)  
 duodenum 11 (3.3) > 11 (> 2.7) 15 (9.4)  
 jejunum/ileum 38 (11.5) 77 (18.9) 38 (23.8)  
 SI NOS* 23 (7.0) 40 (9.8) 13 (8.1)  
 appendix < 11 (< 3.3) < 11(< 2.7) < 11 (< 6.9)  
 cecum 71 (21.5) 71 (17.4) 13 (8.1)  
 colon 80 (24.2) 77 (18.9) 25 (15.6)  
 rectum 52 (15.7) 42 (10.3) < 11 (< 6.9)  
 pancreas < 11 (< 3.3) 40 (9.8) 26 (22.5)  
Tumor stage, n (%)     0.0009
 local 58 (17.5) 73 (17.9) 51 (31.9)  
 regional 135 (40.8) 186 (45.59) 56 (35.0)  
 distant 138 (41.7) 149 (36.5) 53 (33.1)  
Tumor differentiation, n (%)     <.0001
 well-differentiated 82 (24.8) 167 (40.9) 107 (66.9)  
 moderately-differentiated 70 (21.2) 74 (18.1) 19 (11.9)  
 poorly-differentiated 179 (54.1) 167 (40.9) 34 (21.3)  
Comorbidity, n (%)     0.815
 0 138 (41.7) 166 (40.7) 63 (39.4)  
 1–2 142 (42.9) 169 (41.4) 73 (45.6)  
 3+ 51 (15.41) 73 (17.9) 24 (15.0)  
Treatment type, n (%)     <.0001
 surgery 223 (67.4) 331 (81.1) 145 (90.6)  
 endoscopy 21 (6.3) 16 (3.9) < 11 (< 6.9)  
 chemotherapy 25 (7.6) 20 (4.9) < 11 (< 6.9)  
 radiation therapy 12 (3.6) < 11 (< 2.7) < 11 (< 6.9)  
 somatostatin analogue 35 (10.6) 14 (3.4) < 11 (< 6.9)  
 surgery and additional treatment(s) 15 (4.5) > 16 (> 3.9) < 11 (< 6.9)  
NCI designated cancer center*, n (%)     
 yes < 11 (< 3.3) < 11 (< 2.7) 16 (10.0)  
 no 308 (93.1) 383 (93.9) 123 (76.9)  
 unknown > 12 (> 3.6) > 14 (> 3.4) 21 (13.1)  
     <.0001
Academic center*, n (%)     
 yes 143 (43.2) 252 (61.8) 131 (81.9)  
 no 173 (52.3) > 145 (> 35.5) > 18 (> 11.3)  
 unknown 15 (4.5) < 11 (< 2.7) < 11 (< 6.9)  
     <.0001
  1. *Small Intestine Not Otherwise Specified: SI NOS; National Cancer Institute: NCI