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Table 5 Multivariate cox regression analysis of prognostic factors associated with overall survival and disease-free survival

From: Minimal invasive versus open esophagectomy for patients with esophageal squamous cell carcinoma after neoadjuvant treatments

Variables

Overall survival

Disease-free survival

HR

95% CI

P

HR

95% CI

P

Sex

 Female

1

  

  

 Male

2.010

0.994–4.065

0.052

  

Surgical approach

 Open surgery

1

  

1

  

 MIE

0.606

0.384–0.958

0.032

0.848

0.449–1.600

0.610

Location

 Upper third

  

1

  

 Middle third

  

2.179

1.026–4.628

0.043

 Lower third

  

0.835

0.272–2.564

0.752

ypTNM stage

 I

1

  

1

  

 II

1.267

0.617–2.600

0.519

1.245

0.515–3.013

0.626

 III

2.080

1.254–3.451

0.005

0.918

0.444–1.899

0.817

 IV

3.969

1.500–10.505

0.006

1.051

0.236–4.680

0.948

Postoperative therapy

 No

1

  

1

  

 Yes

0.668

0.415–1.074

0.096

0.115

0.057–0.231

< 0.001

  1. HR hazard ratio; CI confidence interval; MIE minimally invasive esophagectomy