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Table 5 Multivariate cox regression analysis of prognostic factors associated with overall survival and disease-free survival

From: Minimal invasive versus open esophagectomy for patients with esophageal squamous cell carcinoma after neoadjuvant treatments

Variables Overall survival Disease-free survival
HR 95% CI P HR 95% CI P
Sex
 Female 1     
 Male 2.010 0.994–4.065 0.052   
Surgical approach
 Open surgery 1    1   
 MIE 0.606 0.384–0.958 0.032 0.848 0.449–1.600 0.610
Location
 Upper third    1   
 Middle third    2.179 1.026–4.628 0.043
 Lower third    0.835 0.272–2.564 0.752
ypTNM stage
 I 1    1   
 II 1.267 0.617–2.600 0.519 1.245 0.515–3.013 0.626
 III 2.080 1.254–3.451 0.005 0.918 0.444–1.899 0.817
 IV 3.969 1.500–10.505 0.006 1.051 0.236–4.680 0.948
Postoperative therapy
 No 1    1   
 Yes 0.668 0.415–1.074 0.096 0.115 0.057–0.231 < 0.001
  1. HR hazard ratio; CI confidence interval; MIE minimally invasive esophagectomy