Table 2 Adverse Events Occurring in rHGG Patients
Adverse Events | Total No. of Patients | No. of Patients | ||
|---|---|---|---|---|
Grade 1 | Grade 2 | Grade 3/4 | ||
Haematologic | ||||
 Anaemia | 13 | 8 | 5 | 0 |
 Neutropenia | 11 | 5 | 6 | 0 |
 Lymphocytopenia | 7 | 2 | 5 | 0 |
 Thrombocytopenia | 7 | 3 | 4 | 0 |
Nonhaematologic | ||||
 Fatigue | 32 | 23 | 9 | 0 |
 Hypertension | 21 | 18 | 3 | 0 |
 Headache | 21 | 17 | 4 | 0 |
 Nausea and vomiting | 13 | 6 | 7 | 0 |
 Seizure | 7 | 7 | 0 | 0 |
 AST* increased | 5 | 2 | 3 | 0 |
 ALT†increased | 4 | 1 | 3 | 0 |