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Table 1 Baseline Characteristics of All Patients (N = 70)

From: Safety and efficacy of Hypofractionated stereotactic radiosurgery for high-grade Gliomas at first recurrence: a single-center experience

Parameter

N

%

Gender

 Male

40

57

 Female

30

43

Age, years

 Median

53

/

 Range

20–76

/

Initial histological WHO grade

 3

21

30

 4

49

70

Interval between HSRS and initial diagnosis (months)

 Median

13.7

/

 Range

1.1–55.3

/

KPS before salvage HSRS

 Median

70

/

 Range

40–90

 

MGMT

 Unmethylated

25

36

 Methylated

9

13

 Unknown

36

51

IDH1 mutation

 Yes

5

7

 No

45

64

 Unknown

20

29

1p19q codeletion

 Yes

1

1

 No

25

36

 Unknown

44

63

Planning tumour volume (cm3)

 Median

16.68

/

 Range

0.81–121.96

/

Concurrent systemic therapy

 TMZ

14

20

 BVZ

28

40

 TMZ + BVZ

7

10

 BSC

21

30

Total

70

100

  1. Abbreviations: WHO World Health Organization, HSRS hypofractionated stereotactic radiosurgery, KPS Karnofsky performance status, MGMT O6-methylguanine-DNA methyltransferase, IDH1 Isocitrate dehydrogenase 1, TMZ Temozolomide, BVZ Bevacizumab, BSC best supportive care