Table 4 Cox Proportional Hazards Regression Model Analysis of Breast Cancer-Specific Survival by Breast Cancer Moleculor Subtype
HR+/HER2- | HR+/HER2+ | HR−/HER2+ | HR−/HER2- | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P | |
Age | ||||||||||||
< 50 | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
≥ 50 | 0.870 | 0.583–1.299 | 0.497 | 0.854 | 0.388–1.880 | 0.695 | 1.573 | 0.707–3.500 | 0.267 | 1.221 | 0.813–1.836 | 0.336 |
Race | ||||||||||||
Black | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
White | 0.738 | 0.466–1.169 | 0.196 | 1.395 | 0.473–4.115 | 0.547 | 1.052 | 0.398–2.779 | 0.918 | 0.870 | 0.570–1.327 | 0.517 |
Other | 0.387 | 0.174–0.860 | 0.020 | 0.446 | 0.049–4.050 | 0.473 | 0.783 | 0.182–3.364 | 0.742 | 0.795 | 0.362–1.742 | 0.566 |
Tumor stage | ||||||||||||
IIIB | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
IIIC | 2.444 | 1.607–3.716 | < 0.001 | 1.800 | 0.776–4.173 | 0.171 | 2.184 | 0.950–5.024 | 0.066 | 2.756 | 1.863–4.075 | < 0.001 |
Grade | ||||||||||||
1/2 | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
3 | 2.241 | 1.473–3.407 | < 0.001 | 2.306 | 0.914–5.816 | 0.077 | 0.611 | 0.281–1.331 | 0.215 | 2.221 | 1.115–4.422 | 0.023 |
Unknown | 2.543 | 1.055–6.128 | 0.038 | 2.534 | 0.494–13.01 | 0.265 | 0.689 | 0.146–3.247 | 0.637 | 2.007 | 0.662–6.085 | 0.218 |
Surgery | ||||||||||||
Partial mastectomy | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
Mastectomy | 0.828 | 0.436–1.574 | 0.565 | 1.444 | 0.189–11.04 | 0.724 | 1.115 | 0.254–4.890 | 0.885 | 2.453 | 0.898–6.700 | 0.080 |
Breast cancer type | ||||||||||||
T4-non-IBC | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
IBC | 1.029 | 0.690–1.534 | 0.888 | 0.678 | 0.307–1.499 | 0.337 | 0.442 | 0.216–0.902 | 0.025 | 1.738 | 1.192–2.534 | 0.004 |