Skip to main content

Table 2 Univariate and multivariate Cox analysis in sarcoma patients

From: Development and validation of an immune gene-set based prognostic signature for soft tissue sarcoma

  Univariate analysis Multivariate analysis
HR 95%CI P HR 95%CI P
Age 1.020 1.004 1.036 0.012 1.025 1.008 1.043 0.004
Sex
 Female         
 Male 0.849 0.565 1.274 0.429     
Race
 Asian     0.412     
 African American 1.108 0.135 9.098 0.924     
 WHITE 0.810 0.111 5.907 0.836     
 Unknown 2.004 0.207 19.378 0.548     
Histological type
 DLP     0.903     
 LMS 0.855 0.515 1.419 0.543     
 MYX 0.730 0.339 1.571 0.421     
 UPS 0.960 0.509 1.810 0.899     
 Other 0.746 0.321 1.734 0.496     
Multifocal indicator
 No     0.002     0.008
 Yes 2.328 1.443 3.754 0.001 2.228 1.324 3.748 0.003
 Unknown 1.220 0.606 2.459 0.577 1.135 0.486 2.651 0.770
Metastasis
 No     < 0.001     < 0.001
 Yes 2.962 1.797 4.880 < 0.001 2.926 1.721 4.972 < 0.001
 Unknown 1.795 1.078 2.987 0.024 1.770 1.005 3.115 0.048
Radiotherapy
 No     0.963     
 Yes 1.012 0.633 1.620 0.959     
 Unknown 1.075 0.638 1.812 0.786     
Surgical margin resection status
 R0     < 0.001     0.005
 R1–2 2.418 1.572 3.719 < 0.001 1.974 1.257 3.099 0.003
 Unknown 2.194 1.156 4.165 0.016 2.099 0.960 4.589 0.063
Tumor site
 Extremity     0.745     
 Other 1.182 0.699 1.997 0.533     
 Retroperitoneum/Upper abdominal 1.193 0.735 1.934 0.475     
Risk 5.192 3.215 8.382 < 0.001 5.362 3.241 8.868 < 0.001
  1. LMS Leiomyosarcoma, DLP Dedifferentiated liposarcoma, UPS Undifferentiated pleomorphic sarcoma, MYX Myxofibrosarcoma