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Table 4 Univariate and multivariate analysis for disease-free survival of patients with primary OSCC

From: Prognostic role of preoperative D-dimer, fibrinogen and platelet levels in patients with oral squamous cell carcinoma

Variables

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Sex

 

0.466

  

 Male

1.00

   

 Female

0.73 (0.32–1.69)

   

Age(years)

 

0.834

  

 <60

1.00

   

  ≥ 60

1.08 (0.52–2.23)

   

T stage

 

0.884

  

 T1 ~ T2

1.00

   

 T3 ~ T4

1.05 (0.53–2.08)

   

N stage

 

0.003

 

0.007

 N0

1.00

 

1.00

 

 N1

0.68 (0.20–2.38)

0.548

0.723 (0.21–2.55)

0.619

 N2

2.20 (1.05–4.57)

0.036

2.46 (1.16–5.23)

0.019

 N3

33.94 (3.65–315.9)

0.002

19.34 (2.00–186.96)

0.010

Clinical stage

 

0.499

  

 I ~ II

1.00

   

 III ~ IV

1.29 (0.62–2.72)

   

Pre. D-dimer

 

0.033

 

0.056

 <500 μg/L

1.00

 

1.00

 

  ≥ 500 μg/L

2.10 (1.06–4.16)

 

1.98 (0.98–3.97)

 

Pre. FIB

 

0.097

 

0.100

 <3.33 g/L

1.00

 

1.00

 

  ≥ 3.33 g/L

1.88 (0.89–3.95)

 

1.94 (0.88–4.26)

 

Pre. PLT

 

0.699

  

 <259.5*10^9/L

1.00

   

  ≥ 259.5*10^9/L

0.86 (0.40–1.84)

   

Surgical type

 

0.732

  

 1

1.00

   

 2

1.40 (0.57–3.44)

0.461

  

 3

1.53 (0.70–3.34)

0.284

  

 4

0.00 (0.00-)

0.983

  

Post.DD change

 

0.791

  

 <1000 μg/L

1.00

   

  ≥ 1000 μg/L

1.16 (0.39–3.46)

   

Post. PLT change

 

0.622

  

 <60*10^9/L

1.00

   

  ≥ 60*10^9/L

1.22 (0.55–2.74)

   
  1. * means multiplication