Fig. 2

Identification of the 4-gene signature and prediction of overall survival (OS) in the training set. a LASSO regression defines 5 critical survival prognostic genes. b Expression differences of the 4 genes, identified by multivariable Cox regression analysis, between 110 USC patients and 113 normal endometrium tissues are analyzed by Wilcox test. P < 0.05 is considered statistically significant. c-e The distribution of risk score, OS, and survival status and the 4 genes expression patterns for the 56 patients in the training set. f Kaplan–Meier analysis to compare OS between patients in the high- and low-risk group in the training set. g ROC analysis of the 4-gene signature and other clinicopathological parameters (age, invasion, node metastasis and stage) for prediction OS in the training set