Skip to main content
Fig. 5 | BMC Cancer

Fig. 5

From: Diallyl thiosulfinate enhanced the anti-cancer activity of dexamethasone in the side population cells of multiple myeloma by promoting miR-127-3p and deactivating the PI3K/AKT signaling pathway

Fig. 5

Cotreatment with diallyl thiosulfinate and dexamethasone (DATS+Dex) promoted miR-3200-5p and miR-127-3p expression. a miR-138, miR-3200-5p, and miR-127-3p expression was significantly lower in side population (SP) cells than in MP cells. Expression of all miRNAs in SP and MP cells of RPMI-8226 and NCI-H929 cell lines was measured using quantitative reverse transcription-polymerase chain reaction (qRT-PCR). b DATS, Dex, and DATS+Dex treatment significantly increased miR-3200-5p and miR-127-3p expression in MM SP cells, but did not affect miR-138 expression, compared with no treatment. *P < 0.05, **P < 0.01, and ***P < 0.001 vs normal group

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us