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Fig. 3 | BMC Cancer

Fig. 3

From: MicroRNA-545 suppresses progression of ovarian cancer through mediating PLK1 expression by a direct binding and an indirect regulation involving KDM4B-mediated demethylation

Fig. 3

Upregulation of miR-545 blocks migration, invasion, and angiogenesis of OC cells. a relative expression of the EMT-related proteins E-cadherin, N-cadherin and Vimentin relative to GAPDH measured by western blot analysis (two-way ANOVA, *p < 0.05); b-c migration (b) and invasion (c) abilities of cells determined by scratch test and Transwell assay, respectively; d angiogenesis ability of HUVECs determined by tube formation assay (one-way ANOVA, *p < 0.05). Repetition = 3. Representative images are provided. Data were collected from three independent experiments and expressed as mean ± SD

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BMC Cancer

ISSN: 1471-2407

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