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Fig. 2 | BMC Cancer

Fig. 2

From: MicroRNA-545 suppresses progression of ovarian cancer through mediating PLK1 expression by a direct binding and an indirect regulation involving KDM4B-mediated demethylation

Fig. 2

Upregulation of miR-545 suppresses growth of OC cells. a miR-545 expression in cells following miR-545 mimic transfection determined by RT-qPCR (one-way ANOVA, *p < 0.05); b viability of cells determined by the MTT assay (one-way ANOVA, *p < 0.05); c DNA replication ability of cells evaluated by the EdU assay (one-way ANOVA, *p < 0.05); d proliferation of cells measured by the colony formation assay (one-way ANOVA, *p < 0.05); e mRNA expression of Bax and Bcl-2 in cells determined by RT-qPCR (one-way ANOVA, *p < 0.05); f apoptosis of cells determined by TUNEL assay (one-way ANOVA, *p < 0.05). Representative images are provided. Data were collected from three independent experiments and expressed as mean ± SD

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BMC Cancer

ISSN: 1471-2407

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