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Table 2 OAR Constraints

From: Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS)

 

3D RT

SBRT 3 fractions

SBRT 5 fractions

Spinal cord

Dmax <45Gy

V18 ≤ 10% for « partial » volume

V23 ≤ 10%

(standard fractionation)

V18 ≤ 0.35 cm3 for « conventional » volume

V23 ≤ 0.35 cm3

 

V12 ≤ 1.2 cm3 for « conventional » volume

V14.5 ≤ 1.2 cm3

Cauda equina

 

V22.5 < 5 cm3

V30 < 5 cm3

 

D2% < 24 Gy

D2% < 32 Gy

Sacral plexus

 

V22 < 3 cm3

V30 < 3 cm3

  1. 3D RT 3 Dimensional Radiation Therapy; SBRT Stereotactic Body radiation Therapy