Associations between I/D polymorphism in the ACE gene and lung cancer: an updated systematic review and a meta-analysis

Table 2 The genotype distribution of ACE I/ D

Author	Sample size (case/control)	Female (%) (case/control)	case					control
Author	Sample size (case/control)	Female (%) (case/control)	I/I	I/D	D/D	I	D	I/I	I/D	D/D	I	D
Peddireddy et al [14]	246/250	28.0/28.0	48	161	37	257	235	111	113	26	335	165
Phukan et al [9]	151/151	45.7 /45.7	61	62	28	184	118	44	68	39	156	146
Ozen et al [16]	52/212	11.5/−	10	30	12	50	54	67	105	40	239	185
Shi et al [12]	120/62	39.2/−	47	49	24	143	97	26	31	5	83	41
Cheon et al [15]	218/121	26.6/42.1	72	116	31	260	178	48	50	23	146	96
Yaren et al [17]	75/85	8.0/9.4	4	39	32	47	103	14	37	34	65	105
Nacak et al [8]	125/165	12.0/48.5	37	50	38	124	126	29	72	64	130	200
Wang et al [13, 21]	34/38	23.5/44.7	10	6	18	26	42	13	18	7	44	32
Zhang et al [18]	47/54	14.9 /29.6	21	21	5	63	31	20	30	4	70	38
Gao et al [11]	684/602	27.2/33.6	351	271	62	973	395	320	253	29	893	311
Devic Pavlic et al [10]	308/353	29.5/38.5	64	148	96	276	340	78	177	98	333	373
Ding et al [19]	121/33	31.4/30.3	55	56	10	166	76	19	10	4	48	18

ISSN: 1471-2407