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Table 2 The genotype distribution of ACE I/ D

From: Associations between I/D polymorphism in the ACE gene and lung cancer: an updated systematic review and a meta-analysis

Author Sample size
(case/control)
Female (%)
(case/control)
case control
I/I I/D D/D I D I/I I/D D/D I D
Peddireddy et al [14] 246/250 28.0/28.0 48 161 37 257 235 111 113 26 335 165
Phukan et al [9] 151/151 45.7 /45.7 61 62 28 184 118 44 68 39 156 146
Ozen et al [16] 52/212 11.5/− 10 30 12 50 54 67 105 40 239 185
Shi et al [12] 120/62 39.2/− 47 49 24 143 97 26 31 5 83 41
Cheon et al [15] 218/121 26.6/42.1 72 116 31 260 178 48 50 23 146 96
Yaren et al [17] 75/85 8.0/9.4 4 39 32 47 103 14 37 34 65 105
Nacak et al [8] 125/165 12.0/48.5 37 50 38 124 126 29 72 64 130 200
Wang et al [13, 21] 34/38 23.5/44.7 10 6 18 26 42 13 18 7 44 32
Zhang et al [18] 47/54 14.9 /29.6 21 21 5 63 31 20 30 4 70 38
Gao et al [11] 684/602 27.2/33.6 351 271 62 973 395 320 253 29 893 311
Devic Pavlic et al [10] 308/353 29.5/38.5 64 148 96 276 340 78 177 98 333 373
Ding et al [19] 121/33 31.4/30.3 55 56 10 166 76 19 10 4 48 18