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Table 2 Patient Population characteristics according to the two groups (no-TOF PET and TOF PET technology)

From: False negative rate at 18F-FDG PET/CT in para-aortic lymphnode involvement in patients with locally advanced cervical cancer: impact of PET technology

Characteristics

no-TOF (N = 141)

TOF (N = 99)

p-value

Age in years, median (range)

45 (21–68)

48 (22–65)

0.009

Tumor stage (FIGO classification)

 IB2

50 (35.5%)

28 (28.3%)

 

 IIa

5 (3.5%)

8 (8.1%)

 

 IIb

73 (51.8%)

48 (48.5%)

0.36

 III

8 (5.7%)

10 (10.1%)

 

 IVa

5 (3.5%)

5 (5%)

 

BMI in kg/m2, median (range)

23 (14–42)

23 (16–35)

0.68

Histologic subtype

 Adenocarcinoma

31 (22%)

18 (19%)

0.62

 Squamous cell carcinoma

110 (78%)

81 (81%)

 

Median size primary tumor

48 mm (20–100)

45.5 mm (10–85)

0.32

Median SUVmax primary tumor

9.8 (3–43)

14.6 (5.6–35)

< 0.001

Pelvic node uptake during PET imaging

 No

93 (66%)

57 (58%)

 

 Yes

48 (34%)

42 (42%)

0.5

 Unilateral pelvic uptake

32

25

 

 Bilateral pelvic uptake

16

17

0.83

Delay in days between PET-surgery, median (range)

15 (1–56)

17 (2–56)

0.22

No of para-aortic nodes removed, median (range)

15 (2–39)

16 (3–40)

0.25

No of patients with positive para-aortic nodes

12 (8.5%)

10 (10%)

0.98

Size of the biggest para-aortic nodes involved, mm

  < 5

5

4

 

  > 5

7

6

0.48

  1. Abbreviations: TOF Time of Flight, FIGO International Federation of Gynecology and Obstetrics, BMI Body Mass Index, SUV Standardized Uptake Value, PET Positron Emission Tomography