Table 1 Univariate Cox regression for OS and LCSS

Age

740

 ≤ 59

180(24.3%)

1

–

1

–

 60–69

200(27.0%)

1.316

0.051

1.213

0.207

 70–79

258(34.9%)

2.034

< 0.001

1.714

< 0.001

  ≥ 80

102(13.8%)

3.015

< 0.001

2.398

< 0.001

Race

740

 White

600(81.1%)

1

–

1

–

 Black

71(9.6%)

0.944

0.714

1.048

0.787

 Other

69(9.3%)

0.902

0.520

1.022

0.900

Gender

740

 Female

440(59.5%)

1

–

1

–

 Male

300(40.5%)

1.302

0.004

1.259

0.024

Grade

494

 Well differentiated

387(78.3%)

1

–

1

–

 Moderately differentiated

86(17.4%)

0.987

0.932

0.948

0.758

 Poorly differentiated/Undifferentiated

21(4.3%)

2.127

0.002

2.236

0.002

Laterality

731

 Only one side

701(95.9%)

1

–

1

–

 Bilateral

30(4.1%)

4.285

< 0.001

5.082

< 0.001

SEER-stage

720

 Localized

353(49.0%)

1

–

1

–

 Regional

172(23.9%)

2.086

< 0.001

2.313

< 0.001

 Distant

195(27.1%)

5.142

< 0.001

6.630

< 0.001

Tstage_8th

591

 T1

209(35.4%)

1

–

1

–

 T2

153(25.9%)

1.706

< 0.001

1.752

0.004

 T3

92(15.6%)

2.545

< 0.001

3.132

< 0.001

 T4

137(23.2%)

4.055

< 0.001

5.923

< 0.001

Nstage_8th

684

 N0

587(85.8%)

1

–

1

–

 N1

33(4.8%)

2.115

< 0.001

2.557

< 0.001

 N2/3

64(9.4%)

3.537

< 0.001

4.080

< 0.001

Mstage_8th

722

 M0

536(74.2%)

1

–

1

–

 M1

186(25.8%)

4.031

< 0.001

4.749

< 0.001

Surgery

740

 No

212(28.6%)

1

–

1

–

 Yes

528(71.4%)

0.235

< 0.001

0.210

< 0.001

Radiation

740

 No

716(96.8%)

1

–

1

–

 Yes

24(3.2%)

1.880

0.005

2.024

0.003

Chemotherapy

740

 No/Unknown

526(71.1%)

1

–

1

–

 Yes

214(28.9%)

2.321

< 0.001

2.829

< 0.001

Marital_status

715

 Divorced

58(8.1%)

1

–

1

–

 Married

451(63.1%)

0.805

0.189

0.761

0.132

 Separated

12(1.7%)

0.816

0.619

0.887

0.786

 Single

77(10.8%)

0.816

0.336

0.727

0.180

 Widowed

117(16.4%)

1.041

0.831

0.969

0.879