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Table 1 Univariate Cox regression for OS and LCSS

From: Development and validation of a nomogram for predicting survival of pulmonary invasive mucinous adenocarcinoma based on surveillance, epidemiology, and end results (SEER) database

Characteristics Number OS LCSS
HR 95.0%CI p HR 95.0%CI p
Age 740       
 ≤ 59 180(24.3%) 1   1  
 60–69 200(27.0%) 1.316 0.999–1.733 0.051 1.213 0.899–1.637 0.207
 70–79 258(34.9%) 2.034 1.584–2.612 < 0.001 1.714 1.301–2.257 < 0.001
  ≥ 80 102(13.8%) 3.015 2.239–4.059 < 0.001 2.398 1.722–3.339 < 0.001
Race 740       
 White 600(81.1%) 1   1  
 Black 71(9.6%) 0.944 0.694–1.285 0.714 1.048 0.748–1.467 0.787
 Other 69(9.3%) 0.902 0.659–1.235 0.520 1.022 0.730–1.431 0.900
Gender 740       
 Female 440(59.5%) 1   1  
 Male 300(40.5%) 1.302 1.089–1.556 0.004 1.259 1.031–1.539 0.024
Grade 494       
 Well differentiated 387(78.3%) 1   1  
 Moderately differentiated 86(17.4%) 0.987 0.733–1.329 0.932 0.948 0.674–1.333 0.758
 Poorly differentiated/Undifferentiated 21(4.3%) 2.127 1.315–3.441 0.002 2.236 1.340–3.732 0.002
Laterality 731       
 Only one side 701(95.9%) 1   1  
 Bilateral 30(4.1%) 4.285 2.946–6.234 < 0.001 5.082 3.482–7.416 < 0.001
SEER-stage 720       
 Localized 353(49.0%) 1   1  
 Regional 172(23.9%) 2.086 1.656–2.628 < 0.001 2.313 1.762–3.038 < 0.001
 Distant 195(27.1%) 5.142 4.133–6.396 < 0.001 6.630 5.177–8.491 < 0.001
Tstage_8th 591       
 T1 209(35.4%) 1   1  
 T2 153(25.9%) 1.706 1.266–2.299 < 0.001 1.752 1.193–2.573 0.004
 T3 92(15.6%) 2.545 1.844–3.512 < 0.001 3.132 2.111–4.648 < 0.001
 T4 137(23.2%) 4.055 3.051–5.389 < 0.001 5.923 4.204–8.343 < 0.001
Nstage_8th 684       
 N0 587(85.8%) 1   1  
 N1 33(4.8%) 2.115 1.438–3.110 < 0.001 2.557 1.708–3.830 < 0.001
 N2/3 64(9.4%) 3.537 2.661–4.701 < 0.001 4.080 3.023–5.507 < 0.001
Mstage_8th 722       
 M0 536(74.2%) 1   1  
 M1 186(25.8%) 4.031 3.310–4.910 < 0.001 4.749 3.836–5.879 < 0.001
Surgery 740       
 No 212(28.6%) 1   1  
 Yes 528(71.4%) 0.235 0.194–0.285 < 0.001 0.210 0.170–0.260 < 0.001
Radiation 740       
 No 716(96.8%) 1   1  
 Yes 24(3.2%) 1.880 1.213–2.915 0.005 2.024 1.275–3.213 0.003
Chemotherapy 740       
 No/Unknown 526(71.1%) 1   1  
 Yes 214(28.9%) 2.321 1.926–2.797 < 0.001 2.829 2.308–3.468 < 0.001
Marital_status 715       
 Divorced 58(8.1%) 1   1  
 Married 451(63.1%) 0.805 0.582–1.113 0.189 0.761 0.533–1.086 0.132
 Separated 12(1.7%) 0.816 0.366–1.819 0.619 0.887 0.373–2.110 0.786
 Single 77(10.8%) 0.816 0.539–1.235 0.336 0.727 0.457–1.158 0.180
 Widowed 117(16.4%) 1.041 0.720–1.505 0.831 0.969 0.644–1.457 0.879