Fig. 3

Comparison of age, gender, stage, TNM stage and prognosis among the DNA methylation subtypes. a, b, c, d, e, and frepresent age, gender, stage score, topography score, lymphocyte infiltration and metastasis distributions for every DNA methylation cluster in the training set. The DNA methylation subtypes are represented by the coordinates of the horizontal axis. g Survival curves for every DNA methylation cluster in the training group. The survival time (years) is represented by the horizontal axis, and the survival probability is represented by the vertical axis. Use the log-rank test to evaluate the statistical significance of differences among clusters. (All figures were generated by “R” (3.6.2) software and Adobe Illustrator (23.0.2) software)