Comparative analysis of patients with upper urinary tract urothelial carcinoma in black-foot disease endemic and non-endemic area

Table 1 Demographic characteristics of UTUC patients in black-foot-disease (BFD) non-endemic and endemic area

Characteristics	Non-endemic N = 527	Endemic N = 667	P-value
Age
< 50	29	47	< 0.001
50 ~ 59	74	111
60 ~ 69	139	210
> 70	259	237
Sex
Male	222	298	0.377
Female	305	369
Smoking
Yes	192	251	0.865
No	69	41
ESRD
Yes	105	63	< 0.001
No	156	223
Non UC tumor
Yes	54	46	0.063
No	469	602
Previous bladder tumor
Yes	30	54	< 0.017
No	231	232
Tumor location
Renal pelvis	369	367	< 0.001
Upper ureter	111	117	0.241
Middle ureter	60	98	0.049
Distal ureter	103	140	0.317
Bladder cuff	7	13	0.354
Tumor size
non-visible	7	3	0.138
< 1 cm	87	22
≥ 1 & < 2 cm	95	43
≥ 2 & < 3 cm	98	45
≥ 3 cm	214	108
Tumor grade
low grade	63	44	0.157
high grade	340	320
Pathologic staging
stage 0a/0is	43	113	< 0.001
stage I	106	150
stage II	112	119
stage III	125	137
stage IV	30	98
Treatment options
NxUx	420	603	0.001
Segmental resection	1	14
Endoscopic	86	9
Adjuvant chemotherapy	53	61	0.153
No operation	22	41
Pre-op mean renal function (eGFR)	37.185	39.216	0.87

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