| |
Univariable
|
Multivariable
|
|---|
| |
HR
|
95% CI
|
P-value
|
HR
|
95% CI
|
P-value
|
|---|
|
Age, years
|
|
< 65
| | | | | | |
|
≥ 65
|
0.869
|
0.643–1.175
|
0.362
| | | |
|
Gender
|
|
Female
| | | | | | |
|
Male
|
0.686
|
0.787–1.439
|
0.686
| | | |
|
TNM Stage
|
|
I
| | |
0.000
| | |
0.000
|
|
II
|
1.470
|
0.938–2.305
|
0.093
|
1.717
|
1.092–2.698
|
0.019
|
|
III
|
1.743
|
0.987–3.079
|
0.055
|
2.078
|
1.172–3.685
|
0.012
|
|
IV
|
2.716
|
1.799–4.101
|
0.000
|
2.963
|
1.957–4.485
|
0.000
|
|
TMB, mut/Mb
|
|
Low
| | | | | | |
|
High
|
1.967
|
1.454–2.660
|
0.000
|
1.500
|
1.085–2.073
|
0.014
|
|
MRS
|
|
Low
| | | | | | |
|
High
|
2.771
|
2.035–3.773
|
0.000
|
2.448
|
1.758–3.409
|
0.000
|
- Abbreviations: CI confidence interval; HR hazard ratio
