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Fig. 2 | BMC Cancer

Fig. 2

From: Comprehensive analysis of genomic mutation signature and tumor mutation burden for prognosis of intrahepatic cholangiocarcinoma

Fig. 2

Protein to protein interaction (PPI) network and functional enrichment pathway of mutated genes. a PPI network of mutated genes; b nodes with an edge of > 20 were considered hub genes; c Gene Ontology analysis. Top 30 enriched terms in GO. Cellular component (CC); biological process (BP); molecular function (MF). d KEGG analysis of mutated genes. The 30 significantly enriched KEGG pathways. Circle size indicates gene numbers, and color represents adj. P-value. Frequencies of major genetic mutations in the enriched pathways are shown

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