Table 2 The associations of NNMT expression with OS in TCGA dataset
Variables | Number of patients | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | P value | ||
Age | 462 | 1.024 (1.013–1.036) | < 0.001 | 1.022 (1.010–1.034) | < 0.001 |
Stage | 0.001 | 0.004 | |||
Early | 33 | 1 | 1 | ||
Late | 429 | 3.478 (1.639–7.381) | 3.044 (1.415–6.550) | ||
Grade | 0.048 | 0.269 | |||
Low | 57 | 1 | 1 | ||
High | 405 | 1.438 (1.003–2.063) | 1.230 (0.852–1.774) | ||
Debulking | 0.030 | 0.304 | |||
Optimal | 344 | 1 | 1 | ||
Suboptimal | 118 | 1.353 (1.030–1.776) | 1.157 (0.876–1.528) | ||
NNMT expression | 0.039 | 0.051 | |||
Low | 415 | 1 | 1 | ||
High | 47 | 1.552 (1.022–2.357) | 1.517 (0.998–2.306) | ||